2006 Legg Mason Tennis Classic – Singles

Andy Roddick was the defending champion, but withdrew due to an Abdominal strain.

Arnaud Clément won in the final 7–6(7–3), 6–2, against Andy Murray.

Seeds
All seeds receive a bye into the second round. • # 🇺🇸 James Blake (third round)

• # 🇺🇸 Andy Roddick (withdrew because of an abdominal strain)

• # 🇦🇺 Lleyton Hewitt (quarterfinals)

• # 🇺🇸 Andre Agassi (second round)

• # 🇸🇰 Dominik Hrbatý (third round)

• # 🇫🇷 Sébastien Grosjean (second round)

• # 🇷🇺 Dmitry Tursunov (semifinals)

• # 🇬🇧 Andy Murray (final)

• # 🇹🇭 Paradorn Srichaphan (second round)

• # 🇫🇷 Julien Benneteau (second round)

• # 🇫🇷 Arnaud Clément (champion)

• # 🇪🇸 Feliciano López (third round)

• # 🇩🇪 Björn Phau (second round)

• # 🇬🇧 Tim Henman (quarterfinals)

• # 🇫🇷 Nicolas Mahut (second round)

• # 🇺🇸 Mardy Fish (quarterfinals)