2006 NASDAQ-100 Open – Women's doubles

The  doubles Tournament at the 2006 NASDAQ-100 Open took place between March 20 and April 6 on the outdoor hard courts of the Tennis Center at Crandon Park in Key Biscayne, United States. Lisa Raymond and Samantha Stosur won the title, defeating Liezel Huber and Martina Navratilova in the final.

Seeds
• # 🇺🇸 Lisa Raymond / 🇦🇺 Samantha Stosur (champions)

• # Cara Black / 🇦🇺 Rennae Stubbs (first round)

• # 🇩🇪 Anna-Lena Grönefeld / 🇺🇸 Meghann Shaughnessy (first round)

• # 🇷🇺 Elena Likhovtseva / 🇷🇺 Vera Zvonareva (first round)

• # 🇸🇰 Daniela Hantuchová / 🇯🇵 Ai Sugiyama (quarterfinals)

• # 🇨🇳 Yan Zi / 🇨🇳 Zheng Jie (first round)

• # Liezel Huber / 🇺🇸 Martina Navratilova (final)

• # 🇯🇵 Shinobu Asagoe / Katarina Srebotnik (semifinals)