2006 Next Generation Adelaide International – Singles

Florent Serra defeated Xavier Malisse, 6–3, 6–4 to win the 2006 Next Generation Adelaide International men's singles competition. Joachim Johansson was the defending champion.

Seeds
• # 🇦🇺 Lleyton Hewitt (second round)

• # 🇸🇰 Dominik Hrbatý (semifinals)

• # 🇪🇸 Tommy Robredo (second round)

• # Mario Ančić (second round)

• # 🇺🇸 James Blake (second round)

• # 🇨🇿 Tomáš Berdych (semifinals)

• # 🇫🇮 Jarkko Nieminen (quarterfinals)

• # 🇦🇷 Juan Ignacio Chela (first round)