2006 Pacific Life Open – Women's singles

Maria Sharapova defeated Elena Dementieva in the final, 6–1, 6–2 to win the women's singles tennis title at the 2006 Indian Wells Masters.

Kim Clijsters was the reigning champion, but chose not to participate that year.

Seeds
All seeds received a bye into the second round. • # 🇧🇪 Justine Henin-Hardenne (semifinals)

• # 🇺🇸 Lindsay Davenport (fourth round)

• # 🇷🇺 Maria Sharapova (champion)

• # 🇷🇺 Elena Dementieva (final)

• # 🇷🇺 Anastasia Myskina (fourth round)

• # 🇮🇹 Flavia Pennetta (third round)

• # 🇩🇪 Anna-Lena Grönefeld (quarterfinals)

• # Ana Ivanovic (quarterfinals)

• # 🇫🇷 Nathalie Dechy (second round)

• # 🇷🇺 Dinara Safina (quarterfinals)

• # 🇷🇺 Maria Kirilenko (third round)

• # 🇫🇷 Tatiana Golovin (third round)

• # 🇪🇸 Anabel Medina Garrigues (second round)

• # 🇯🇵 Ai Sugiyama (fourth round)

• # Jelena Janković (second round)

• # 🇨🇿 Klára Koukalová (second round)

• # 🇦🇷 Gisela Dulko (quarterfinals)

• # 🇨🇿 Lucie Šafářová (third round)

• # Martina Hingis (semifinals)

• # 🇫🇷 Marion Bartoli (third round)

• # 🇮🇱 Shahar Pe'er (fourth round)

• # 🇷🇺 Anna Chakvetadze (fourth round)

• # 🇨🇴 Catalina Castaño (second round)

• # 🇨🇿 Iveta Benešová (second round)

• # 🇮🇹 Mara Santangelo (second round)

• # 🇮🇱 Anna Smashnova (third round)

• # 🇵🇱 Marta Domachowska (third round)

• # 🇮🇳 Sania Mirza (third round)

• # 🇺🇸 Amy Frazier (second round)

• # 🇫🇷 Émilie Loit (second round)

• # 🇺🇸 Laura Granville (third round)

• # 🇺🇸 Jill Craybas (second round)

Seeds
• # 🇮🇹 Maria Elena Camerin (qualifying competition, Lucky loser)

• # 🇭🇺 Melinda Czink (first round)

• # 🇩🇪 Martina Müller (first round)

• # 🇧🇾 Anastasiya Yakimova (qualifying competition)

• # 🇨🇿 Eva Birnerová (qualifying competition)

• # 🇨🇳 Yuan Meng (qualified)

• # 🇺🇦 Yuliana Fedak (qualified)

• # 🇷🇺 Anastasia Rodionova (qualified)

• # 🇺🇸 Bethanie Mattek (qualified)

• # 🇦🇷 María Emilia Salerni (first round)

• # 🇺🇦 Kateryna Bondarenko (first round)

• # 🇫🇷 Camille Pin (qualified)

• # 🇦🇹 Yvonne Meusburger (first round)

• # 🇮🇹 Nathalie Viérin (qualifying competition)

• # 🇯🇵 Rika Fujiwara (qualifying competition)

• # 🇺🇦 Mariya Koryttseva (first round)

• # Ivana Lisjak (qualified)

• # 🇨🇿 Kateřina Böhmová (qualified)

• # 🇧🇾 Victoria Azarenka (qualifying competition)

• # Hsieh Su-wei (qualifying competition)

• # 🇻🇪 Milagros Sequera (qualified)

• # 🇺🇿 Varvara Lepchenko (qualifying competition)

• # 🇺🇸 Lilia Osterloh (qualifying competition)

• # 🇦🇺 Nicole Pratt (qualified)

Qualifiers
• # 🇨🇿 Kateřina Böhmová

• # 🇱🇺 Anne Kremer

• # Ivana Lisjak

• # 🇧🇾 Anastasiya Yakimova

• # 🇦🇺 Nicole Pratt

• # 🇨🇳 Yuan Meng

• # 🇺🇦 Yuliana Fedak

• # 🇷🇺 Anastasia Rodionova

• # 🇺🇸 Bethanie Mattek

• # 🇺🇸 Jessica Kirkland

• # 🇧🇾 Tatiana Poutchek

• # 🇫🇷 Camille Pin

Lucky loser

 * 1) 🇮🇹 Maria Elena Camerin