2006 RCA Championships – Singles

Robby Ginepri was the defending champion, but lost to Andy Roddick in the semifinals.

James Blake won in the final 4–6, 6–4, 7–6(7–5), against Andy Roddick.

Seeds
All seeds receive a bye into the second round. • # 🇺🇸 James Blake (champion)

• # 🇺🇸 Andy Roddick (final)

• # Fernando González (quarterfinals)

• # 🇺🇸 Robby Ginepri (semifinals)

• # 🇩🇪 Tommy Haas (third round)

• # 🇸🇰 Dominik Hrbatý (second round)

• # 🇷🇺 Dmitry Tursunov (third round)

• # 🇹🇭 Paradorn Srichaphan (quarterfinals)

• # 🇧🇪 Xavier Malisse (semifinals)

• # 🇫🇷 Nicolas Mahut (quarterfinals)

• # 🇺🇸 Paul Goldstein (third round)

• # 🇱🇺 Gilles Müller (quarterfinals)

• # 🇺🇸 Kevin Kim (second round)

• # 🇺🇸 Vince Spadea (third round)

• # 🇷🇺 Igor Kunitsyn (third round)

• # 🇷🇺 Marat Safin (second round)