2006 Tennis Channel Open – Singles

Wayne Arthurs was the defending champion, but did not participate that year.

James Blake won the title, defeating Lleyton Hewitt 7–5, 2–6, 6–3 in the final.

Seeds

 * 1) 🇦🇺 Lleyton Hewitt (final)
 * 2) 🇩🇪 Nicolas Kiefer (second round, withdrew because of an illness)
 * 3) 🇪🇸 Tommy Robredo (quarterfinals)
 * 4) 🇺🇸 Robby Ginepri (first round)
 * 5) 🇺🇸 James Blake (champion)
 * 6) 🇫🇷 Gaël Monfils (first round)
 * 7) 🇩🇪 Tommy Haas (withdrew because of a shoulder injury)
 * 8) 🇪🇸 Fernando Verdasco (first round)