2006 U.S. Men's Clay Court Championships – Singles

Seeds
A champion seed is indicated in bold text while text in italics indicates the round in which that seed was eliminated.


 * 1) 🇺🇸 Andy Roddick (quarterfinals)
 * 2) 🇺🇸 James Blake (first round)
 * 3) 🇺🇸 Robby Ginepri (first round)
 * 4) 🇨🇾 Marcos Baghdatis (second round, retired because of a back injury)
 * 5) 🇩🇪 Tommy Haas (semifinals, retired because of a wrist injury)
 * 6) 🇵🇪 Luis Horna (first round)
 * 7) 🇺🇸 Paul Goldstein (semifinals)
 * 8) 🇦🇷 Juan Mónaco (first round)