2007 Campbell's Hall of Fame Tennis Championships – Singles

Mark Philippoussis was the defending champion, but did not participate. Fabrice Santoro defeated Nicolas Mahut in the final 6–4, 6–4.

The event saw first seed Mardy Fish being knocked out of the first round by qualifier Aisam-ul-Haq Qureshi, continuing the tradition of the first seeds never winning the Newport event. Fish had once knocked out the first seed when he was a qualifier.

Seeds
• # 🇺🇸 Mardy Fish (first round)

• # 🇺🇸 Vince Spadea (quarterfinals)

• # 🇫🇷 Michaël Llodra (withdrew)

• # 🇫🇷 Fabrice Santoro (champion)

• # 🇫🇷 Nicolas Mahut (final)

• # 🇷🇺 Teymuraz Gabashvili (first round)

• # 🇷🇺 Igor Kunitsyn (first round)

• # 🇩🇪 Michael Berrer (second round)