2008 ABN AMRO World Tennis Tournament – Singles

Mikhail Youzhny was the defending champion, but lost in the first round to Janko Tipsarević.

None of the 8 seeded players reached quarter-finals. Michaël Llodra won his only ATP 500 singles final 6–7(3–7), 6–3, 7–6(7–4), against Robin Söderling.

Seeds
• # 🇪🇸 Rafael Nadal (second round)

• # 🇷🇺 Nikolay Davydenko (second round)

• # 🇪🇸 David Ferrer (second round)

• # 🇷🇺 Mikhail Youzhny (first round)

• # 🇨🇿 Tomáš Berdych (second round)

• # 🇬🇧 Andy Murray (first round)

• # 🇪🇸 Juan Carlos Ferrero (first round)

• # 🇨🇾 Marcos Baghdatis (first round)