2008 ECM Prague Open – Men's singles

The men's singles of the 2008 ECM Prague Open tournament was played on clay in Prague, Czech Republic.

Dušan Lojda was the defending champion, but lost in first round to Augustin Gensse.

Jan Hernych won the title by defeating Lukáš Dlouhý 4–6, 6–2, 6–4 in the final.

Seeds
• # 🇨🇿 Jiří Vaněk (first round)

• # 🇦🇷 Brian Dabul (quarterfinals)

• # 🇫🇷 Nicolas Devilder (first round)

• # 🇦🇷 Leonardo Mayer (second round)

• # 🇷🇴 Adrian Cruciat (first round)

• # 🇮🇱 Harel Levy (semifinals)

• # 🇩🇪 Dominik Meffert (quarterfinals)

• # 🇨🇿 Lukáš Dlouhý (final)