2008 French Open – Women's singles

Ana Ivanovic defeated Dinara Safina in the final, 6–4, 6–3 to win the women's singles tennis title at the 2008 French Open. It was her first and only major singles title. With the win, Ivanovic also became the world No. 1; Maria Sharapova, Jelena Janković and Svetlana Kuznetsova were also in contention for the top ranking. Ivanovic dropped only one set during the tournament, to Janković in the semifinals.

Justine Henin was the three-time reigning champion and reigning world No. 1, but she retired from the sport in May 2008. This left Serena Williams as the only former French Open champion in the draw; when Williams was defeated in the third round by Katarina Srebotnik, a first-time French Open champion was guaranteed.

Safina reached the final after having come back from a set and match point down in both of her fourth round and quarterfinal matches, against Sharapova and Elena Dementieva, respectively.

This was also the first major main draw appearance for future world No. 2 and two-time Wimbledon champion Petra Kvitová, who lost to Kaia Kanepi in fourth round. With that win, Kanepi became the first Estonian to reach a major quarterfinal.

Seeds
• 🇷🇺 Maria Sharapova (fourth round)

• 🇷🇸 Ana Ivanovic (champion)

• 🇷🇸 Jelena Janković (semifinals)

• 🇷🇺 Svetlana Kuznetsova (semifinals)

• 🇺🇸 Serena Williams (third round)

• 🇷🇺 Anna Chakvetadze (second round)

• 🇷🇺 Elena Dementieva (quarterfinals)

• 🇺🇸 Venus Williams (third round)

• 🇫🇷 Marion Bartoli (first round)

• Patty Schnyder (quarterfinals)

• 🇷🇺 Vera Zvonareva (fourth round)

• 🇭🇺 Ágnes Szávay (third round)

• 🇷🇺 Dinara Safina (final)

• 🇵🇱 Agnieszka Radwańska (fourth round)

• 🇨🇿 Nicole Vaidišová (first round)

• 🇧🇾 Victoria Azarenka (fourth round)

• 🇮🇱 Shahar Pe'er (first round)

• 🇮🇹 Francesca Schiavone (third round)

• 🇫🇷 Alizé Cornet (third round)

• 🇦🇹 Sybille Bammer (first round)

• 🇷🇺 Maria Kirilenko (second round)

• 🇫🇷 Amélie Mauresmo (second round)

• 🇺🇦 Alona Bondarenko (first round)

• 🇫🇷 Virginie Razzano (first round)

• 🇷🇺 Nadia Petrova (third round)

• 🇮🇹 Flavia Pennetta (fourth round)

•  Katarina Srebotnik (fourth round)

• 🇸🇰 Dominika Cibulková (third round)

• 🇪🇸 Anabel Medina Garrigues (third round)

•  Caroline Wozniacki (third round)

• 🇯🇵 Ai Sugiyama (second round)

• 🇮🇹 Karin Knapp (third round)