2008 Hall of Fame Tennis Championships – Singles

Fabrice Santoro was the defending champion, and won in the final 6–3, 7–5, against Prakash Amritraj.

Seeds
The top four seeds receive a bye into the second round. • # 🇺🇸 Mardy Fish (second round)

• # 🇫🇷 Fabrice Santoro (champion)

• # 🇫🇷 Nicolas Mahut (second round)

• # 🇷🇺 Igor Kunitsyn (quarterfinals)

• # 🇺🇸 John Isner (first round)

• # 🇺🇸 Donald Young (second round)

• # 🇨🇦 Frank Dancevic (semifinals)

• # Kevin Anderson (second round)