2008 Legg Mason Tennis Classic – Singles

Andy Roddick was the defending champion, but lost in the quarterfinals to Viktor Troicki.

Juan Martín del Potro won in the final 6–3, 6–3, against Viktor Troicki.

Seeds
• # 🇺🇸 Andy Roddick (quarterfinals)

• # 🇦🇷 Juan Martín del Potro (champion)

• # 🇪🇸 Feliciano López (first round)

• # 🇩🇪 Tommy Haas (semifinals)

• # 🇺🇸 Mardy Fish (first round)

• # 🇷🇺 Marat Safin (first round, retired due to a neck pain)

• # 🇫🇷 Marc Gicquel (first round)

• # 🇪🇸 Marcel Granollers (first round)