2008 Mercedes Cup – Singles

Rafael Nadal was the defending champion, but was forced to withdraw due to a knee injury.

Unseeded Juan Martín del Potro won in the final 6–4, 7–5, against second-seeded Richard Gasquet.

Seeds
The top four seeds receive a bye into the second round. • # 🇪🇸 Rafael Nadal (withdrew due to a knee injury)

• # 🇫🇷 Richard Gasquet (final)

• # 🇪🇸 Nicolás Almagro (second round)

• # 🇩🇪 Philipp Kohlschreiber (quarterfinals)

• # 🇮🇹 Simone Bolelli (second round)

• # 🇦🇷 Agustín Calleri (semifinals)

• # 🇦🇷 José Acasuso (first round)

• # 🇦🇷 Eduardo Schwank (semifinals)