2008 Prairie View A&M Panthers football team

The 2008 Prairie View A&M Panthers football team represented Prairie View A&M University as a member of the Southwestern Athletic Conference (SWAC) during the 2008 NCAA Division I FCS football season. Led by fifth-year head coach Henry Frazier III, the Panthers compiled an overall record of 9–1, with a mark of 7–1 in conference play, and finished second in the SWAC West Division.