2008 St. Petersburg Open – Singles

Andy Murray was the defending champion, and won in the final 6–1, 6–1, against Andrey Golubev.

Seeds
• # 🇬🇧 Andy Murray (champion)

• # 🇷🇺 Nikolay Davydenko (second round, withdrew due to a wrist injury)

• # 🇪🇸 Fernando Verdasco (semifinals)

• # 🇷🇺 Mikhail Youzhny (second round)

• # Marin Čilić (first round)

• # 🇷🇺 Dmitry Tursunov (first round)

• # Mario Ančić (first round)

• # 🇷🇺 Marat Safin (second round)