2009–10 in Uruguayan football

Primera División
Source: RSSSF
 * Champion: Peñarol (48th title)
 * Top scorer: Antonio Pacheco (23 goals)
 * International qualifiers:
 * Copa Libertadores:
 * Group Stage: Peñarol and Nacional
 * Preliminary Round: Liverpool
 * Copa Sudamericana:
 * First Stage: River Plate and Defensor Sporting
 * Second Stage: Peñarol
 * Widest winning margin: Montevideo Wanderers 7–1 Cerro Largo (April 4, 2010), Atenas 0–6 Nacional (March 14, 2010) and Liverpool 7–1 Tacuarembó (October 22, 2009)
 * Highest scoring: Danubio 4–5 Tacuarembó (January 24, 2010)
 * Most wins: Nacional and Peñarol (22)
 * Fewest wins: Atenas (6)
 * Most draws: Central Español and River Plate (10)
 * Fewest draws: Atenas and Danubio (3)
 * Most losses: Atenas (21)
 * Fewest losses: Peñarol (4)
 * Most goals scored: Peñarol (70)
 * Fewest goals scored: Atenas (25)
 * Most goals conceded: Atenas (62)
 * Fewest goals conceded: Nacional (28)
 * Best goal difference: Nacional (+38)
 * Worst goal difference: Atenas (-37)
 * Relegated: Atenas, Cerro Largo and Cerrito

Second Division

 * Segunda División champion: El Tanque Sisley
 * Top scorer: Daniel Martínez (10 goals)
 * Apertura champion: Miramar Misiones
 * Top scorer: Jesús Benítez (9 goals)
 * Clausura champion: Bella Vista
 * Top scorer: Marcelo Fernández and José Pérez Bach (8 goals)

First promotion play-offs

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Promoted teams
Source: RSSSF
 * El Tanque Sisley
 * Bella Vista
 * Miramar Misiones

Senior team
This section covers Uruguay's senior team matches from 1 August 2009 until the end of the 2010 FIFA World Cup, on 11 July 2010.