2009 Open GDF Suez – Singles

Anna Chakvetadze was the defending champion, but chose not to participate that year.

Amélie Mauresmo won the title, defeating Elena Dementieva in the final 7–6(9–7), 2–6, 6–4. This was Mauremso's final WTA singles title before her retirement at the end of 2009.

Seeds
• # 🇺🇸 Serena Williams (semifinals, withdrew due to knee injury)

• # 🇷🇸 Jelena Janković (semifinals)

• # 🇷🇺 Elena Dementieva (final)

• # 🇵🇱 Agnieszka Radwańska (quarterfinals)

• # 🇫🇷 Alizé Cornet (quarterfinals)

• # Patty Schnyder (second round)

• # 🇪🇸 Anabel Medina Garrigues (first round)

• # 🇫🇷 Amélie Mauresmo (champion)