2010–11 Maltese First Division

The 2010–11 Maltese First Division (also known as 2010–11 BOV 1st Division due to sponsorship reasons) began on 23 October 2010 and ended on 1 May 2011.

Due to a in-season change regarding the league system, the third-placed team of this season will be promoted to the Maltese Premier League, along with the regular two promotees.

Teams
These teams will contest the 2010–11 season:
 * Balzan Youths
 * Dingli Swallows
 * Lija Athletic
 * Melita
 * Mosta
 * Mqabba
 * Msida Saint-Joseph
 * Pietà Hotspurs
 * St. Andrews
 * St. George's

Changes from previous season

 * Marsaxlokk and Vittoriosa Stars were promoted to the Premier League. They were replaced with Dingli Swallows and Msida Saint-Joseph, both relegated from 2009–10 Maltese Premier League
 * St. Patrick and last-placed San Gwann were relegated to the 2010–11 Maltese Second Division. They were replaced with Lija Athletic and St. Andrews.