2010–11 Wyoming Cowboys basketball team

The 2010–11 Wyoming Cowboys basketball team represented the University of Wyoming during the 2010–2011 NCAA Division I men's basketball season. The Cowboys was coached by Heath Schroyer, he was fired on February 8, 2011. Fred Langley replaced Heath Schroyer as their interim coach. They played their home games at the Arena-Auditorium in Laramie, Wyoming. The Cowboys are a member of the Mountain West Conference. They finished the season 10–21, 3–13 in Mountain West play and lost in the first round of the 2011 Mountain West Conference men's basketball tournament to TCU.

Preview
The Cowboys were picked to finish eighth in the Mountain West Conference.

Schedule and results
!colspan=9 style=| Exhibition

!colspan=9 style=| Regular Season

!colspan=10 style=| Mountain West tournament