2010 İstanbul Cup – Singles

Vera Dushevina was the defending champion but lost to Jarmila Groth in the quarterfinals.

Anastasia Pavlyuchenkova won the title, defeating Elena Vesnina in the final 5–7, 7–5, 6–4.

Seeds
• # 🇮🇹 Francesca Schiavone (second round)

• # 🇨🇿 Petra Kvitová (first round)

• # 🇷🇺 Anastasia Pavlyuchenkova (champion)

• # 🇰🇿 Yaroslava Shvedova (first round)

• # 🇧🇬 Tsvetana Pironkova (second round)

• # 🇩🇪 Andrea Petkovic (semifinals)

• # 🇨🇿 Klára Zakopalová (first round)

• # Patty Schnyder (first round)