2010 AON Open Challenger – Singles

Alberto Martín was the defending champion but decided not to participate this year.

Fabio Fognini won the Italian final, where he defeated Potito Starace 6–4, 6–1.

Seeds
• # 🇮🇹 Potito Starace (final)

• # 🇮🇹 Andreas Seppi (semifinals)

• # 🇮🇹 Fabio Fognini (champion)

• # 🇷🇺 Teymuraz Gabashvili (second round)

• # 🇮🇹 Filippo Volandri (quarterfinals)

• # 🇪🇸 Pablo Andújar (quarterfinals)

• # Nicolás Massú (first round)

• # 🇮🇹 Simone Bolelli (semifinals)