2010 Aberto Santa Catarina de Tenis – Singles

Marcelo Demoliner was the defending champion, but he lost against Ricardo Mello in the first round. Marcos Daniel won in the final 7–5, 6–7(5), 6–4 against Bastian Knittel.

Seeds
• # Nicolás Massú (quarterfinals)

• # Blaž Kavčič (second round)

• # 🇧🇷 Ricardo Mello (second round)

• # 🇧🇷 Marcos Daniel (champion)

• # 🇧🇷 Thiago Alves (second round)

• # 🇧🇷 Júlio Silva (semifinals)

• # 🇦🇷 Juan Pablo Brzezicki (second round)

• # 🇦🇷 Diego Junqueira (semifinals)