2010 Abierto Internacional Varonil Casablanca Cancún – Singles

Nicolás Massú was the defending champion but decided not to participate. Pere Riba won the tournament after defeating Carlos Berlocq 6–4, 6–0 in the final.

Seeds
• # 🇦🇷 Carlos Berlocq (final)

• # 🇪🇸 Pere Riba (champion)

• # 🇪🇸 Rubén Ramírez Hidalgo (semifinals)

• # 🇦🇷 Brian Dabul (quarterfinals)

• # 🇦🇷 Horacio Zeballos (quarterfinals)

• # 🇸🇮 Grega Žemlja (first round)

• # 🇦🇷 Máximo González (withdrew)

• # 🇫🇷 Éric Prodon (semifinals)