2010 Atlanta Tennis Championships – Singles

Robby Ginepri was the defending champion, but lost in the second round to fellow American and eventual champion Mardy Fish. Fish won his second title of 2010 and in July by defeating compatriot John Isner 4–6, 6–4, 7–6(7–4).

Seeds
The top four seeds receive a bye into the second round. • # 🇺🇸 Andy Roddick (semifinals)

• # 🇺🇸 John Isner (final)

• # 🇦🇺 Lleyton Hewitt (second round)

• # 🇦🇷 Horacio Zeballos (second round)

• # 🇷🇸 Janko Tipsarević (first round)

• # 🇺🇸 Mardy Fish (champion)

• # 🇧🇪 Xavier Malisse (quarterfinals)

• # 🇩🇪 Benjamin Becker (first round)