2010 BMW Open – Singles

Tomáš Berdych was the defender of title; however, he lost to Philipp Petzschner in the quarterfinals. Mikhail Youzhny won in the final 6–3, 4–6, 6–4 against Marin Čilić.

Former world no. 7 Mario Ančić played his last professional match of his career, losing in straight sets to Daniel Köllerer in the first round. He would announce his retirement the following year due to recurrence of his mononucleosis.

Seeds
• # Marin Čilić (finals)

• # 🇷🇺 Mikhail Youzhny (champion)

• # 🇨🇿 Tomáš Berdych (quarterfinals)

• # 🇩🇪 Philipp Kohlschreiber (quarterfinals)

• # 🇨🇾 Marcos Baghdatis (semifinals)

• # 🇪🇸 Nicolás Almagro (quarterfinals)

• # 🇫🇷 Julien Benneteau (first round)

• # 🇩🇪 Benjamin Becker (second round)