2010 BSI Challenger Lugano – Singles

Stanislas Wawrinka was the defending champion, and he won in the final 6–7(2), 6–2, 6–1 against Potito Starace.

Seeds
• # Stanislas Wawrinka (champion)

• # 🇮🇹 Potito Starace (final)

• # Frederico Gil (first round)

• # Rui Machado (first round)

• # 🇧🇷 Thiago Alves (first round)

• # 🇷🇺 Teymuraz Gabashvili (semifinals)

• # 🇮🇹 Filippo Volandri (second round retired)

• # 🇪🇸 Alberto Martín (semifinals)