2010 Bank Austria-TennisTrophy – Singles

Jürgen Melzer was the defending champion. He successfully defended his last year's title by beating Lucky loser and his compatriot, Andreas Haider-Maurer 6–7(10–12), 7–6(7–4), 6–4 in the final match.

Seeds
The top four seeds received a bye into the second round. • # 🇦🇹 Jürgen Melzer (champion)

• # Marin Čilić (quarterfinals)

• # 🇪🇸 Nicolás Almagro (semifinals)

• # 🇨🇾 Marcos Baghdatis (quarterfinals)

• # Ernests Gulbis (withdrew due to personal reasons)

• # 🇪🇸 Guillermo García-López (first round)

• # 🇩🇪 Philipp Kohlschreiber (quarterfinals, withdrew because of a right abductor injury)

• # 🇦🇷 Juan Ignacio Chela (quarterfinals)