2010 Bank of the West Classic – Singles

Marion Bartoli was the defending champion, but lost to Victoria Azarenka in the quarterfinals.

Azarenka went on to win the title, defeating Maria Sharapova in the final 6–4, 6–1.

Seeds
The top two seeds receive a bye into the second round. • # 🇦🇺 Samantha Stosur (semifinals)

• # 🇷🇺 Elena Dementieva (quarterfinals)

• # 🇵🇱 Agnieszka Radwańska (semifinals)

• # 🇫🇷 Marion Bartoli (quarterfinals)

• # 🇷🇺 Maria Sharapova (final)

• # 🇮🇱 Shahar Pe'er (second round)

• # 🇧🇪 Yanina Wickmayer (quarterfinals)

• # 🇧🇾 Victoria Azarenka (champion)