2010 Banka Koper Slovenia Open – Singles

Dinara Safina was the defending champion, but she chose not to participate.

Anna Chakvetadze won the title, defeating Johanna Larsson in the final, 6–1, 6–2. This was the final WTA singles title that Chakvetadze won before her retirement in 2013.

Seeds
• # 🇷🇸 Jelena Janković (second round, retired due to left ankle injury)

• # 🇨🇿 Petra Kvitová (first round)

• # 🇷🇺 Anastasia Pavlyuchenkova (quarterfinals)

• # 🇮🇹 Sara Errani (second round)

• # 🇸🇰 Dominika Cibulková (first round)

• # 🇷🇺 Vera Dushevina (quarterfinals)

• # Polona Hercog (semifinals)

• # 🇸🇪 Sofia Arvidsson (first round)