2010 Brasil Open – Singles

Tommy Robredo was the defending champion, but he chose to compete in the 2010 ABN AMRO World Tennis Tournament instead.

Juan Carlos Ferrero won in the final 6–1, 6–0 against Łukasz Kubot.

Seeds
• # 🇪🇸 Juan Carlos Ferrero (champion)

• # 🇪🇸 Albert Montañés (second round)

• # 🇧🇷 Thomaz Bellucci (quarterfinals)

• # 🇷🇺 Igor Andreev (semifinals)

• # 🇷🇴 Victor Hănescu (second round)

• # Pablo Cuevas (quarterfinals)

• # 🇦🇷 Horacio Zeballos (first round, retired)

• # 🇫🇷 Richard Gasquet (withdrew due to a back injury)

Seeds
• # 🇪🇸 Pere Riba (first round)

• # 🇷🇴 Victor Crivoi (second round)

• # Rui Machado (qualified)

• # 🇪🇸 Alberto Martín (second round)

• # 🇦🇷 Brian Dabul (first round)

• # 🇪🇸 Rubén Ramírez Hidalgo (first round)

• # 🇪🇸 David Marrero (first round)

• # 🇧🇷 Júlio Silva (first round)

Qualifiers
• # 🇮🇹 Filippo Volandri

• # 🇧🇷 Rogério Dutra Silva

• # Rui Machado

• # 🇦🇷 Carlos Berlocq

Lucky loser
• # 🇪🇸 Pablo Andújar