2010 Brazil Open Series – Singles

Ricardo Mello was the defending champion and he reached the final, but he lost to Dominik Meffert 4–6, 7–6(3), 2–6.

Seeds
• # Nicolás Massú (second round)

• # Blaž Kavčič (first round)

• # 🇧🇷 Ricardo Mello (final)

• # 🇧🇷 Marcos Daniel (semifinals, retired)

• # 🇧🇷 Thiago Alves (semifinals)

• # 🇧🇷 João Souza (first round)

• # Ramón Delgado (second round)

• # 🇧🇷 Júlio Silva (first round)