2010 Cellular South Cup – Singles

Victoria Azarenka was the defending champion but she chose to compete in 2010 Dubai Tennis Championships instead. Maria Sharapova won in the final 6–2, 6–1 against Sofia Arvidsson.

Seeds
• # 🇷🇺 Maria Sharapova (champion)

• # 🇺🇸 Melanie Oudin (quarterfinals)

• # 🇪🇪 Kaia Kanepi (quarterfinals)

• # 🇨🇿 Lucie Hradecká (first round)

• # 🇨🇿 Petra Kvitová (semifinals)

• # 🇩🇪 Kristina Barrois (first round)

• # 🇺🇸 Vania King (second round)

• # 🇬🇧 Elena Baltacha (quarterfinals)