2010 Challenger Salinas Diario Expreso – Singles

Santiago Giraldo was the defending champion, but chose to not participate this year.

Brian Dabul won in the final 6–3, 6–2 against Nicolás Massú.

Seeds
• # Nicolás Massú (final)

• # 🇧🇷 Thiago Alves (first round)

• # 🇦🇷 Sebastián Decoud (second round)

• # 🇨🇴 Carlos Salamanca (second round)

• # 🇦🇷 Brian Dabul (champion)

• # 🇲🇽 Santiago González (second round)

• # 🇦🇷 Diego Junqueira (quarterfinals)

• # 🇧🇷 João Souza (quarterfinals)