2010 Copa Sudamericana final stages

The finals stages of the 2010 Copa Sudamericana de Clubes are the Round of 16, Quarterfinals, Semifinals, and Finals. Teams from the Round of 16 onwards were seeded depending on which Second Stage tie they win (i.e. the winner of Match O1 has the 1 seed).

Bracket
Note: The bracket was adjusted according to the rules of the tournament so that the two Brazilian teams would face each other in the semifinals.

Round of 16



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Match C1
''San José 3–3 Newell's Old Boys on points. Newell's Old Boys advanced on goal difference.''

Match C2
''Independiente 3–3 Defensor Sporting on points. Independiente advanced on goal difference.''

Match C3
''Peñarol 3–3 Goiás on points. Goiás advanced on away goals.''

Match C4
Palmeiras advanced on points 6–0.

Match C5
''Santa Fe 3–3 Atlético Mineiro on points. Atlético Mineiro advanced on goal difference.''

Match C6
''Avaí 3–3 Emelec on points. Avaí advanced on goal difference.''

Match C7
''Deportes Tolima 3–3 Banfield on points. Deportes Tolima advanced on goal difference.''

Match C8
''LDU Quito 3–3 Unión San Felipe on points. LDU Quito advanced on goal difference.''

Quarterfinals



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Match S1
LDU Quito advanced on points 4–1.

Match S2
Note: The second leg was played at a neutral venue since Independiente received a one-match stadium ban after crowd trouble at their home ground during their Round of 16 second leg against Defensor Sporting.

''Independiente 2–2 Deportes Tolima on points. Independiente advanced on away goals.''

Match S3
Goiás advanced on points 4–1.

Match S4
Palmeiras advanced on points 4–1.

Semifinals



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Match F1
''Independiente 3–3 LDU Quito on points. Independiente advanced on away goals.''

Match F2
''Palmeiras 3–3 Goiás on points. Goiás advanced on away goals.''

Finals
Note: In the final, the away goals rule would not be applied, and extra time would be played if necessary.

''Independiente 3–3 Goiás on points. Independiente won on penalties.''