2010 Copa Sudamericana preliminary stages

The preliminary stages of the 2010 Copa Sudamericana de Clubes are:
 * First Stage, contested by 16 teams in 8 two-legged ties. The winner of each tie will advance to the Second Stage.
 * Second Stage, contested by 30 teams, 8 of whom advanced from the First Stage, in 15 two-legged ties. The winner of each tie will advance to the Round of 16, joining the defending champion, LDU Quito.

First stage



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Match A
''Colo-Colo 3–3 Universitario on points. Universitario advanced on away goals.''

Match B
''River Plate 3–3 Guaraní on points. Guaraní advanced on away goals.''

Match C
Barcelona advanced on points 6–0.

Match D
Atlético Huila advanced on points 4–1.

Match E
Oriente Petrolero advanced on points 4–1.

Match F
Defensor Sporting advanced on points 4–1.

Match G
''Universidad San Martín 3–3 Deportivo Quito on points. Universidad San Martín advanced on away goals.''

Match H
''Santa Fe 3–3 Deportivo Lara on points. Santa Fe advanced on goal difference.''

Second stage



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Match O1
San José advanced on points 4-1.

Match O2
Independiente advanced on points 4–1.

Match O3
Peñarol advanced on points 6–0.

Match O4
''Palmeiras 3–3 Vitória on points. Palmeiras advanced on goal difference.''

Match O5
Santa Fe advanced on points 4–1.

Match O6
''Avaí 3–3 Santos on points. Avaí advanced on goal difference.''

Match O7
''Deportes Tolima 3–3 Oriente Petrolero on points. Deportes Tolima advanced on goal difference.''

Match O9
''Unión San Felipe 3–3 Guaraní on points. Unión San Felipe advanced 8–7 on penalties.''

Match O10
Banfield advanced on points 4–1.

Match O11
''Emelec 3–3 Universidad San Martín on points. Emelec advanced on goal difference.''

Match O12
Atlético Mineiro advanced on points 4–1.

Match O13
Universitario advanced on points 4–1.

Match O14
Goiás advanced on points 4–1.

Match O15
Note: This is the largest margin of victory in the history of the Copa Sudamericana.

''Sport Huancayo 3–3 Defensor Sporting on points. Defensor Sporting advanced on goal difference.''

Match O16
Newell's Old Boys advanced on points 4–1.