2010 Dubai Tennis Championships – Men's singles

Novak Djokovic was the defending champion, and won in the final 7–5, 5–7, 6–3, against Mikhail Youzhny.

Seeds
• # Roger Federer (withdrew due to a lung infection)

• # 🇷🇸 Novak Djokovic (champion)

• # 🇬🇧 Andy Murray (second round)

• # 🇷🇺 Nikolay Davydenko (second round, retired due to a left wrist injury)

• # 🇫🇷 Jo-Wilfried Tsonga (second round)

• # Marin Čilić (quarterfinals)

• # 🇷🇺 Mikhail Youzhny (final)

• # 🇫🇷 Gilles Simon (first round)

Seeds
• # 🇷🇺 Igor Kunitsyn (qualified)

• # 🇷🇸 Dušan Vemić (first round)

• # 🇩🇪 Björn Phau (qualified)

• # 🇦🇹 Stefan Koubek (qualified)

• # 🇹🇷 Marsel İlhan (first round)

• # 🇨🇿 Jan Hernych (qualifying competition, lucky loser)

• # 🇮🇳 Somdev Devvarman (qualified)

• # 🇺🇦 Ivan Sergeyev (qualifying competition)

Qualifiers
• # 🇷🇺 Igor Kunitsyn

• # 🇮🇳 Somdev Devvarman

• # 🇩🇪 Björn Phau

• # 🇦🇹 Stefan Koubek

Lucky loser
• # 🇨🇿 Jan Hernych