2010 FINA World Swimming Championships (25 m) – Women's 100 metre butterfly

The Women's 100 Butterfly at the 10th FINA World Swimming Championships (25m) took place 18–19 December 2010 in Dubai, United Arab Emirates. The heats and semifinals were swum 18 December; the final on 19 December.

61 individuals swam the event.

Records
Prior to the competition, the existing world and championship records were as follows.

The following records were established during the competition:

Semifinals
Semifinal 1

Semifinal 2