2010 FINA World Swimming Championships (25 m) – Women's 400 metre freestyle

The Women's 400 Freestyle at the 10th FINA World Swimming Championships (25m) was swum on 17 December 2010 in Dubai, United Arab Emirates. 47 swimmers raced in the preliminary heats, with the top-8 advancing to a final that evening.

Records
Prior to the competition, the existing world and championship records were as follows.

The following records were established during the competition: