2010 French Open – Wheelchair women's singles

Three-time defending champion Esther Vergeer defeated Sharon Walraven in the final, 6–0, 6–0 to win the women's singles wheelchair tennis title at the 2010 French Open. Vergeer lost no sets and only four games en route to the title.

Seeds

 * 1) Esther Vergeer (champion)
 * 2) 🇫🇷 Florence Gravellier (semifinals)