2010 Gerry Weber Open – Singles

Tommy Haas was the defending champion, but did not participate as he was recovering from hip surgery. Lleyton Hewitt won 3–6, 7–6(7–4), 6–4 against five-time champion Roger Federer in the final to claim the title.

Seeds
• # Roger Federer (final)

• # 🇷🇺 Nikolay Davydenko (second round)

• # 🇷🇺 Mikhail Youzhny (first round)

• # 🇪🇸 Juan Carlos Ferrero (first round)

• # 🇨🇿 Radek Štěpánek (withdrew due to an infection)

• # 🇦🇹 Jürgen Melzer (second round)

• # 🇨🇾 Marcos Baghdatis (first round)

• # 🇦🇺 Lleyton Hewitt (champion)