2010 Guangzhou International Women's Open – Singles

Shahar Pe'er was the defending champion, but chose not to participate that year.

Jarmila Groth won her first WTA tour title, defeating Alla Kudryavtseva in the final 6–1, 6–4. Groth won the tournament without dropping a single set.

Seeds
• # 🇦🇺 Jarmila Groth (champion)

• # Chan Yung-jan (first round)

• # 🇺🇿 Akgul Amanmuradova (second round)

• # 🇯🇵 Ayumi Morita (second round)

• # Chang Kai-chen (second round)

• # 🇷🇸 Bojana Jovanovski (first round)

• # 🇮🇹 Alberta Brianti (second round)

• # Chanelle Scheepers (second round)