2010 Internazionali Femminili di Palermo – Doubles

Nuria Llagostera Vives and María José Martínez Sánchez were the defending champions, but both chose not to participate. Alberta Brianti and Sara Errani won the final against Jill Craybas and Julia Görges 6–4, 6–1.

Seeds
• # Natalie Grandin / 🇨🇿 Vladimíra Uhlířová (first round)

• # 🇺🇿 Akgul Amanmuradova / 🇷🇴 Ioana Raluca Olaru (first round)

• # 🇪🇸 Arantxa Parra Santonja / 🇨🇿 Renata Voráčová (quarterfinals)

• # 🇺🇦 Mariya Koryttseva / 🇧🇾 Darya Kustova (quarterfinals)