2010 Jackson State Tigers football team

The 2010 Jackson State Tigers football team represented Jackson State University as a member of the East Division of the Southwestern Athletic Conference (SWAC) during the 2010 NCAA Division I FCS football season. Led by fifth-year head coach Rick Comegy, the Tigers compiled an overall record of 8–3 with a mark of 6–3 in conference place, sharing the SWAC East Division title with Alabama State.