2010 Movistar Open – Singles

Fernando González was the defending champion, but he lost to Thomaz Bellucci 3–6, 6–4, 6–3 in the semifinals. Thomaz Bellucci won in the final 6–2, 0–6, 6–4 against Juan Mónaco.

Seeds
• # Fernando González (semifinals)

• # 🇦🇷 Juan Mónaco (final)

• # 🇧🇷 Thomaz Bellucci (champion)

• # Pablo Cuevas (first round)

• # 🇦🇷 Horacio Zeballos (first round)

• # 🇦🇷 José Acasuso (second round, retired because of a left knee injury)

• # 🇩🇪 Simon Greul (first round)

• # 🇮🇹 Potito Starace (first round)

Seeds
• # 🇦🇷 Brian Dabul (second round)

• # 🇮🇹 Flavio Cipolla (second round)

• # 🇪🇸 Rubén Ramírez Hidalgo (qualified)

• # 🇪🇸 David Marrero (qualified)

• # 🇧🇷 Júlio Silva (first round)

• # 🇪🇸 Pablo Andújar (second round)

• # 🇦🇷 Gastón Gaudio (second round)

• # 🇷🇴 Adrian Ungur (qualifying competition)

Qualifiers
• # 🇦🇷 Juan-Martín Aranguren

• # 🇧🇷 João Souza

• # 🇪🇸 Rubén Ramírez Hidalgo

• # 🇪🇸 David Marrero