2010 NCAA Division II baseball tournament

The 2010 NCAA Division II baseball tournament was the postseason tournament hosted by the NCAA to determine the national champion of baseball among its Division II members at the end of the 2010 NCAA Division II baseball season.

The final, eight-team double elimination tournament, also known as the College World Series, was played at the USA Baseball National Training Complex in Cary, North Carolina from May 22–29, 2010.

Southern Indiana defeated UC San Diego in the championship game, 6–4, to claim the Screaming Eagles' first Division II national title.

College World Series

 * Note: Losers of each round were shifted to the opposing bracket.