2010 Odlum Brown Vancouver Open – Women's singles

Stéphanie Dubois was the defending champion but she lost in the quarterfinals to Irina Falconi. Fourth seed Jelena Dokić from Australia defeated France's Virginie Razzano to claim the title.

Seeds
• # Chan Yung-jan (second round)

• # Chang Kai-chen (first round)

• # 🇦🇺 Alicia Molik (first round)

• # 🇦🇺 Jelena Dokić (champion)

• # 🇨🇦 Stéphanie Dubois (quarterfinals)

• # 🇫🇷 Virginie Razzano (final)

• # 🇺🇸 Lilia Osterloh (quarterfinals)

• # 🇮🇳 Sania Mirza (second round)