2010 Open de Moselle – Singles

Gaël Monfils was the defending champion, but he withdrew before his match against German qualifier Mischa Zverev. Gilles Simon won the title, by defeating Zverev in the final, 6–3, 6–2.

Seeds
The first four seeds received a bye to the first round. • # Marin Čilić (quarterfinals)

• # 🇫🇷 Gaël Monfils (withdrew)

• # Ivan Ljubičić (second round)

• # 🇫🇷 Richard Gasquet (semifinals, withdrew due to a fever)

• # 🇫🇷 Michaël Llodra (withdrew)

• # 🇩🇪 Philipp Kohlschreiber (semifinals)

• # 🇪🇸 Tommy Robredo (quarterfinals)

• # 🇫🇷 Gilles Simon (champion)