2010 Pan Pacific Swimming Championships – Women's 4 × 100 metre freestyle relay

The women's 4 × 100 metre freestyle relay competition at the 2010 Pan Pacific Swimming Championships took place on August 20 at the William Woollett Jr. Aquatics Center. The last champion was the United States.

This race consisted of eight lengths of the pool. Each of the four swimmers completed two lengths of the pool. The first swimmer had to touch the wall before the second could leave the starting block.

Records
Prior to this competition, the existing world and Pan Pacific records were as follows:

Results
All times are in minutes and seconds.

Heats
Heats weren't performed, as only five teams had entered.

Final
The final was held on August 20, at 20:06.