2010 Rai Open – Singles

Sebastián Decoud was the defending champion, but chose to compete in Pereira instead. Filippo Volandri won in the final 6–4, 7–5, against Lamine Ouahab.

Seeds
• # 🇦🇹 Daniel Köllerer (first round)

• # 🇪🇸 Rubén Ramírez Hidalgo (first round)

• # 🇧🇪 Christophe Rochus (quarterfinals)

• # 🇨🇿 Jan Hernych (second round)

• # 🇧🇪 Kristof Vliegen (first round)

• # 🇪🇸 Albert Ramos-Viñolas (second round)

• # 🇷🇴 Adrian Ungur (first round)

• # 🇺🇸 Jesse Witten (second round)